Safety data sheet creation date october2009 revision date 18january2018 revision number 5 1. During the reaction, the substitution of ethoxyl group is controlled to a commercially useful range of 45% to 52% ethoxyl or2. Ethyl cellulose article about ethyl cellulose by the. Ethyl cellulose general information, process, products. Ethyl cellulose containing 4648% or more of ethoxyl groups is freely soluble in ethanol, methanol, toluene and ethyl acetate. Extensional flow response in capillary breakup, jetting and in a crossslot extensional rheometer vivek sharma 1,2, simon j. The food additive ethyl cellulose may be safely used in food in accordance with the following prescribed conditions. Influence of the functionalization pattern of ethyl cellulose on the interactions with polystyrene latex particles in aqueous mixtures. If inhaled if breathed in, move person into fresh air. Recently, the formation of liquid crystalline systems from solutions in water and organic solvents of cellulose and its derivatives, including hydroxypropyl cellulose hpc, ethyl cellulose ec, cellulose di and triacetates ca has. It can be prepared by treatment of cellulose with dimethyl sulfate and ethyl chloride in the presence of an alkali. Scaling concepts in polymer physics, cornell university press, ithaka 1979. The ethyl cellulose of each grade can in turn form 30 kinds of products according to the. Thermal study of ethyl cellulose coating films used for modified release mr dosage forms.
Sublime treatment caring hair oil with soft touch by dow sublime treatment caring hair oil with soft touch is a hair serum that. This msds has been prepared according to the hazard criteria of t he controlled products regulations cpr and the msds contains all of the information required by the cpr. Metals and arsenic specifications revised at the 57th jecfa 2001. Ethyl cellulose article about ethyl cellulose by the free. Ethyl cellulose containing less than 4648% of ethoxyl groups is freely soluble in. Typically, aqualon ec is used as a nonswellable, insoluble component in matrix or coating systems. Pdf 43 hydrolysis of cellulose and hemicellulose researchgate.
Prevent from entering into soil, ditches, sewers, waterways andor groundwater. Safety data sheet creation date oct2009 revision date 18jan2018 revision number 5 1. The food additive ethyl cellulose may be safely used in animal feed in accordance with the following prescribed conditions. Chemically, it is a derivative of cellulose with ethyl and methyl groups attached by ether linkages. This invention is concerned with improvements in the production of cellulose ethers particularly ethyl cellulose. The number of ethyl groups can vary depending on the manufacturer. Bacterial translocation and intestinal capillary permeability following major liver resection in the rat. Identification of the substancemixture and of the companyundertaking 1.
Sds of ethyl cellulose, safety data sheets, cas 9004573. Ethyl cellulose is soluble in varying amounts in certain organic solvents, depending upon the ethoxyl content. Bp11254 casno 141786 synonyms acetic acid ethyl ester recommended use laboratory chemicals. Tri ethyl citrate tec and dibutyl sebacate dbs were the plasticizers used while hydroxypropyl methyl cellulose hpmc was used as the poreformer. The rheology of aqueous solutions of ethyl hydroxyethyl cellulose ehec and its hydrophobically modified analogue hmehec ii.
Ethylcellulose is a freeflowing, white to light tan powder used in the pharmaceutical and food manufacturing industries. Ethyl cellulose is thermoplastic, with a softening point of 140170c and a melting point of 160210c. It is mainly used as a thinfilm coating material for coating paper, vitamin and medical pills, and for. Identification product name ethyl cellulose, ethoxyl. The rheology of aqueous solutions of ethyl hydroxyethyl. Ethyl cellulose is a derivative of cellulose in which some of the hydroxyl groups on the repeating glucose units are converted into ethyl ether groups.
Firstaid measures material safety data sheet the dow chemical company. Amorphous ethyl cellulose ec of varying viscosities 10, 22, and 300 cp were obtained from aldrich ec 10 and ec 22 and dow chemical ethocel 300 with ethoxyl content of 48%, a product commonly derived from cellulose by etheration 48. Hydroxy propyl methyl cellulose, ethyl cellulose, hec. Its use is presently requested in the formulation of food supplements in dry applications e. Ethyl cellulose prepared at the 26th jecfa 1982, published in fnp 25 1982 and fnp 52 1992. Ethyl cellulose or ethylcellulose is a derivative of cellulose in which some of the hydroxyl groups on the repeating glucose units are converted into ethyl ether groups. Ethylcellulose aqueous dispersion impurities definition ethylcellulose aqueous dispersion is a colloidal dispersion ofdelete the following. Ethyl cellulose ec is a nontoxic, stable, compressible, inert, hydrophobic polymer that has been widely used to prepare pharmaceutical dosage forms.
Safety data sheet according to 29cfr19101200 and ghs rev. Kenji kamide, in cellulose and cellulose derivatives, 2005. The ethyl cellulose of each grade can in turn form 30 kinds of products according to the differences in the viscosity. Ethyl cellulose ec is a partly oethylated cellulose ether derivative. Triethyl citrate tec and dibutyl sebacate dbs were the plasticizers used while hydroxypropyl methyl cellulose hpmc was used as the poreformer. Dow center midland, mi 48674 usa customer information number. C 6 h 7 o 2 oh 3x oc 2 h 5 x n, the ethyl ether of cellulose produced by the reaction of alkaline cellulose with ethyl chloride, ethyl cellulose takes the form of an odorless, tasteless. Aqueous solutions of ethyl hydroxyethyl cellulose and hydrophobic modified ethyl hydroxyethyl cellulose polymer. Ethyl cellulose containing less than 4648% of ethoxyl groups is freely. Each model has special grade and quality requirements according to the special uses. Aqualon ethylcellulose ec is a cellulose ether distinguished by its versatility. Walocel mw 40000 pfv 50 methyl hydroxyethyl cellulose issue date. Firstaid measures eye contact rinse immediately with plenty of water, also under the. Aqualon ethylcellulose ec is a cellulose ether made by the reaction of ethyl.
Keyword search register account settings wishlist order status history. The properties of ethyl cellulose sustained release products, including film coated tablets 7, microspheres 8,9, microcapsules 10 and matrix tablets. Ungraded products supplied by spectrum are indicative of a grade suitable for general industrial. Material safety data sheetmsds ethyl acetate synonyms. Skin contact wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Firstaid measures eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Gels from modified hydroxyethyl cellulose and ionic surfactants.
Walocel mw 40000 pfv 50 methyl hydroxyethyl cellulose company identification the dow chemical company 2030 willard h. Cas 9004675 methyl cellulose 100 % percentages are by weight section 4. Ethyl methyl cellulose is a thickener, vegetable gum, foaming agent and emulsifier. The rheology of aqueous solutions of ethyl hydroxy ethyl cellulose ehec and its hydrophobically modified analogue hmehec ii.
Ethyl cellulose ec is an inert, biocompatible, nonionic water insoluble polymer widely used to prepare slowrelease formulations of drugs due to its controlled release property 4. Ethyl cellulose material safety data sheet cas no 900457. Ethyl cellulose cas no 9004573 material safety data. Perez, conformations of the hydroxymethyl group in. Keep in mind that any accidents involving a chemical will require an sds to be provided to emergency personnel, and to the attending physician so proper. Sigmaaldrich offers a number of ethyl cellulose products. Preparation of ethyl cellulose nanoparticles by solvent. Ethyl cellulose is compatible with other cellulose ethers, mineral oils, vegetable oils, most plasticizers, and many natural and synthetic resins. Its 5% soliquoid shows neutral to litmus test paper. Read and understand the safety data sheet sds before using this product. Ethyl cellulose, ethoxyl content 50%, 100 cps revision date 19jan2018 ethylcellulose 9004573 48 4. Preparation of ethyl cellulose nanoparticles by solventdisplacement using the conventional method and a recirculation system 175 drugs, but holds the appealing potential of being able. Sigmaaldrich material safety data sheet date printed. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet emergency telephone number chemtreco, inside the usa.
Assay methyl ethyl cellulose contains, on the dried basis, not less than 3. Effect of hydroxypropyl methylcellulose and ethyl cellulose. Aqualon ec can be used to coat one or more active ingredients of a tablet to prevent them from. Hazards identification this product is not classified as dangerous according to ec criteria.
The macroscopic properties of aqueous solutions of hydroxyethyl cellulose hec and of modified. First aid measures description of first aid measures. Hercules company can be divided into three typesk,n,and t. Ethyl cellulose containing less than 4648% of ethoxyl groups is freely soluble in tetrahydrofuran, methyl acetate and aromatic hydrocarbon ethanol mixtures. In case of skin contact wash off with soap and plenty of water. Show this safety data sheet to the doctor in attendance. Its e number is e465 chemically, it is a derivative of cellulose with ethyl and methyl groups attached by ether. Aqualon ec is soluble in a wide range of organic solvents. Ethyl cellulose cas no 9004573 material safety data sheet sds msds. Ethyl cellulose cas no 9004573 manufacturers, suppliers. Ethyl cellulose is a widely used excipient in pharmaceutical applications. Ethyl cellulose ec is a kind of white grains or powder, having no smell or tastes. Department of food science, cornell university, ithaca, new york, 14853.
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